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TherapyMatch-D trial

What the study is about

This is a small pilot trial. It checks if an app using AI can help pick the best therapy for people with depression in high intensity services.

Which therapies are compared

Two common therapies are used: cognitive behavioural therapy (CBT) and person-centred experiential therapy (PCE or counselling for depression). Both work well.

How the app is used

In the app group, the app gives a personalised therapy suggestion. Therapists and patients use this in their decision on what treatment to follow. In the other group which is the control group, the app will be used as a tool to collect data.

What the trial checks

The study wants to see if matching certain groups of people to one therapy helps reduce depression.

Who sponsors it

Rotherham, Doncaster and South Humber NHS Foundation Trust.

Recruitment end date: 31 May 2026.

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Published: November 25, 2025